Metrics details. Tissue infections or skin, skin structure, and deep seated soft tissue infections are general terms for infections of the entire skin layer including the subcutaneous and muscle tissue layers and their respective fascia structures.
Infections of the different mediastinal fascias mediastinitis and retroperitoneal fascia infections also belong to this category. Due to the variability of their clinical presentation, skin and soft tissue infections can be classified according to different features. The following aspects can be used for classification:. The incidence of skin and soft tissue infections in which MRSA methicillin-resistent Staphylococcus aureus is involved has been steadily increasing over the past 15 years.
These wounds should be treated according to the same open treatment principles as other infected wounds. Since these infections are often superficial contaminations, antibiotic therapy is not indicated.
If systemic infection occurs in form of MRSA sepsis, antibiotic therapy is indicated. Subcutaneous tissue e. The multilayer infection of skin and subcutaneous tissue is defined as cellulitis. For example Herpes viruses, such as the herpes simplex virus types I and II diseases: orolabial herpes, genital herpes, eczema herpeticum.
The British microbiologist Kingston developed a therapeutically relevant classification in for surgical patients, which is based on the urgency for a surgical intervention see Kingston and Seal The term "complicated skin and skin structure infections" developed as a result of multinational pharmaceutical trials by the American Food and Drug Administration FDA. Such infections are defined according to the following criteria:.
