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Twokidney, oneclip 2K1C hypertensive rats were given sinapine for four weeks, with weekly blood pressure monitoring. The impact of sinapine on vascular endothelial cell A10 calcium and potassium channels was assessed using the patch-clamp technique. Sinapine has an antihypertensive function and achieves this process through multiple targets. Hypertension increases the risks of heart, brain, and kidney disease 1 , 2 , 3 , 4. The World Health Organization predict that 1. Currently, hypertension is the most important modifiable morbidity.
Prevention of hypertension is critically essential. Antihypertensive drugs can reduce the morbidity and mortality caused by hypertension 6. There are multiple classes of antihypertensive medications.
However, some drugs have adverse effects 7 , 8. Medicinal plants, with fewer side effects and various targets, are potential candidates for antihypertensive therapy 9 , 10 , A clinical study has proven that consuming cruciferous vegetables prevents and treats cardiovascular diseases, including hypertension 12 , Previously, we conducted a series of studies on the biology of cruciferous plants. We found that giving rats the aqueous ethanolic extract of rapeseed meal resulted in a decrease in blood pressure.
