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Official websites use. Share sensitive information only on official, secure websites. Studies suggest spinal manipulation reduces migraine burden, but none have evaluated effects of a comprehensive package of chiropractic care on migraine frequency, disability, and quality of life QOL.
We conducted a pilot randomized trial comparing an expert-panel-validated, multimodal chiropractic care CC intervention plus enhanced usual care EUC to EUC alone among 61 adult women with episodic migraine. EUC was comprised of usual medical care and migraine education literature. Primary aims assessed feasibility of recruitment, retention and adherence to the protocol, and adverse events.
Fifty-seven We observed 98 nonserious adverse events of which 35 were musculoskeletal complaints and 45 were related to migraine attacks.
Recruitment, retention, and adherence to the interventions are feasible. We estimated incremental cost-effectiveness ratios ICERs from societal and health-care perspectives using 8 randomized trials performed in the United States.
We used a 2-stage approach to individual participant data meta-analysis with quality-adjusted life years QALYs as the effectiveness measure.