Clade 2. Since April , the U. CDC confirmed 67 human cases through genome sequence analysis. Data in some of these cases showed the amino acid substitution NA-SN known to slightly reduce susceptibility to the neuraminidase inhibitor oseltamivir in laboratory tests.
In one case, a different change in the polymerase acidic PA protein was detected. Full details. Since November , the Eastern parts of the Democratic Republic of the Congo DRC continue to see cases of the mpox virus Clade Ib that is also spreading through regional travel to neighboring countries in Central and Eastern Africa, incl. Burundi, Kenya, Rwanda and Uganda. Outside of Africa, imported cases continue to be reported, incl.
According to the CDC , early data indicate that a large proportion of Clade Ib cases among adults are associated with intimate human contact, including via ongoing transmission believed to be occurring in some countries where the virus is not normally found. Melbourne, Australia An advisory group of experts taking part in a meeting organized by the WHO Global Influenza Programme between September analyzed influenza virus surveillance data generated by the WHO Global Influenza Surveillance and Response System GISRS , and issued on 27 September , recommendations on the composition of the influenza vaccines for the following influenza season.
These recommendations are used by the national vaccine regulatory agencies and the pharmaceutical companies to develop, produce and license influenza vaccines. The Arbovirus Summit discussed the urgent need to strengthen integrated arbovirus surveillance and management. Held at the recently inaugurated GISAID Academy April , the Summit showcased innovations in vector control strategies, breakthroughs in antivirals and vaccine development and explore the implementation of global genomic surveillance of arbovirus as a tool for monitoring the effectiveness of intervention strategies as well as viral spread and evolution.
Yogyakarta, June. Global leaders reflected on the need to coordinate and strengthen resources during future pandemics. With the core principals of timely international sharing of health data for protecting populations against lethal infectious disease outbreaks and adherence to scientific etiquette of acknowledgement of the source of data has resulted in global trust and confidence in GISAID.
