Lichen planus LP is a chronic inflammatory condition affecting the skin and mucosal surfaces. There are several clinical types:. It has no strong racial predilection. Lichen planus is a T-cell mediated autoimmune disorder in which inflammatory cells attack an unknown protein within the skin and mucosal keratinocytes.
Lichenoid inflammation is also notable in graft-versus-host disease. Vitamin D deficiency may be associated with oral lichen planus. Its association with other types of LP remains unexplored. Lichen planus may cause a small number or many lesions on the skin and mucosal surfaces. The usual presentation of the disease is classical lichen planus. Symptoms can range from none uncommon to intense itch. Papular lichen planus coalescing into plaques on the wrist PLP-patient1.
Flat topped, shiny, polygonal papules of lichen planus on the volar wrist PLP-patient1. A plaque of lichen planus showing Wickham striae. Papular lichen planus with Koebner phenomenum in skin of colour. Papular lichen planus with a linear Koebner lesion due to a scratch.
The mouth is often the only affected area and often involves the inside of the cheeks and the sides of the tongue, but the gums and lips may also be involved.
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Reticulate buccal mucosal lichen planus. Lacy reticulated lichen planus covering the entire tongue. Erosive lichen planus on the lateral border of the tongue. Reticulate and violaceous lichen planus on the lower lip. Lichen planus may affect the labia majora, labia minora, and vaginal introitus. Presentation includes:.
