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Official websites use. Share sensitive information only on official, secure websites. Published: July 7, Author Contributions: Drs Sapiano and Epstein had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Conflict of Interest Disclosures: Dr Dumyati reported receiving personal fees from Seres Therapeutics outside the submitted work. Dr Lynfield reported being a coeditor of a textbook on infectious disease surveillance and an associate editor of the American Academy of Pediatrics Red Book outside the submitted work.
No other disclosures were reported. Disclaimer: The findings and conclusions in this article are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
Contributors did not receive compensation outside of usual salary. What types of health care exposures occur during the 30 days before hospitalization of a patient with sepsis or septic shock, and how common are these exposures? After controlling for other factors, an association was found between underlying comorbidities, such as cirrhosis, immunosuppression, and vascular disease, and day mortality.
The findings suggest that future efforts to improve outcomes among patients with sepsis and septic shock would benefit from examination of health maintenance practices and recent health care exposures as potential opportunities among high-risk patients.
Current information on the characteristics of patients who develop sepsis may help in identifying opportunities to improve outcomes. Most recent studies of sepsis epidemiology have focused on changes in incidence or have used administrative data sets that provided limited patient-level data.