To browse Academia. Nirgundi oil and Castor oil are used in the treatment of inflammation and Rheumatoid Arthritis. Nirgundi oil is obtained from the leaves of the Vitex Negundo Linn. The formulations containing both oils produce synergistic effect. Nirgundi oil contains Luteolin and Castor oil has Ricinoleic acid which are responsible for the anti-inflammatory action. The study aims to perform physicochemical and phytochemical investigation of the oils available in local market as its standardization parameters for detection of the adulterations in the oil.
The results obtained can be utilized as a quality determination tool for marketed oils. Vitex negundo has been used in massage oil as well as in traditional ayurveda as a potent pain reliever.
The traditional Method of obtaining oil is simply based on taking water as the medium for extraction. The water extract obtained is then boiled with oil,till the water is completely evaporated. Here our aim is to replace water by different organic solvents and obtain oil which has much better efficacy than the traditionally extracted oil. The idea here is to obtain more efficacious oil than the marketed sample which is majorly extracted using water as solvent.
Here the different organic solvents used are methanol, ethanol, petroleum ether and chloroform. The oil obtained was checked for its anti-inflammatory activity with the carrageenan induced rat paw edema.
The prepared oil was compared with the marketed sample of mahanarayan oil. The methanolic extract has showed to be having high extract yield in literature. Journal of Natural Product Research and Applications. The objective of our work in this study is the extraction and characterization of castor oil Ricinus communis L physicochemical characterization for a better appreciation of the oil.
