Official websites use. Share sensitive information only on official, secure websites. Each patient underwent from a minimum of 3 to a maximum of 4 treatments, with an Nd:YAP nm medical device, every four weeks, with 3- and 6-month follow-up, in these areas: back, abdomen, breast, flanks, lower limbs, buttocks, and thighs. Manchester Scar Scale assessed stretch marks improvement. Side effects, patient pain, and SD overall appearance improvement were also recorded for all patients.
Digital photographs measured the aesthetic results. Treatment was well-tolerated pain score 1. The total mean pretreatment Manchester Scar Scale score decreased from An Nd:YAP nm laser seems to be a safe and effective treatment, showing a higher security profile with no side effects.
Striae distensae SD , or stretch marks, are prevalent skin lesions with linear features of atrophic skin [ 1 ]. To date, these skin scars characterized by epidermal atrophy are of great interest in the aesthetic field [ 2 , 3 ]. In SD, there is a rapid elongation of the skin, which causes a reorganization of reticular collagen [ 4 ].
At the epidermal level, there is a loss of dermal papillae and the formation of network crests, while the dermis shows a de-crease in the components of the extracellular matrix ECM ; fibronectin, fibrillin, collagen, and elastin [ 5 , 6 ].
The dermis consists of a matrix of elastin and collagen [ 7 ]. In healthy skin, it is possible to observe that collagen fibrils, organized in densely packed bundles [ 8 ], permit the skin to stretch and then return to its native shape [ 9 , 10 , 11 ]. The collagen bundles are separated following SD development, not allowing the collagen fibrils to reform the bundles.
